human UBC shRNA silencing AAV

Name
AAV-h-UBC-shRNA

Cat No
shAAV-226985

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human UBC.

shAAV-226985

AAV-h-UBC-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human UBC (ubiquitin C). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

HMG20

Description (Vector)

UBC represents a ubiquitin gene, ubiquitin C. The encoded protein is a polyubiquitin precursor. Conjugation of ubiquitin monomers or polymers can lead to various effects within a cell, depending on the residues to which ubiquitin is conjugated. Ubiquitination has been associated with protein degradation, DNA repair, cell cycle regulation, kinase modification, endocytosis, and regulation of other cell signaling pathways.

Gene ID

7316

Gene Name (Vector)

ubiquitin C

Gene Symbol

UBC

HGNC ID

HGNC:12468

ORF Size (aa)

2058

ORF Size (bp)

2058 bp

RefSeq ID

NM_021009

RefSeq Synonyms

NM_021009, BC039193,

Species

human

UniGene ID

Hs.520348

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.