human TUSC3 shRNA silencing AAV

Name 
AAV-h-TUSC3-shRNA
Cat No 
shAAV-226869
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human TUSC3.

shAAV-226869
AAV-h-TUSC3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TUSC3 (tumor suppressor candidate 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
D8S1992; M33; MRT22; MRT7; N33; OST3A
Description (Vector)
TUSC3 is a candidate tumor suppressor gene. It is located within a homozygously deleted region of a metastatic prostate cancer. The gene is expressed in most nonlymphoid human tissues including prostate, lung, liver, and colon. Expression was also detected in many epithelial tumor cell lines. Two transcript variants encoding distinct isoforms have been identified for this gene.
Gene ID
7991
Gene Name (Vector)
tumor suppressor candidate 3
Gene Symbol
TUSC3
HGNC ID
HGNC:30242
ORF Size (aa)
1044
RefSeq ID
NM_006765
RefSeq Synonyms
NM_178234, NM_006765, BC010370,
Species
human
UniGene ID
Hs.591845

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.