human TULP3 shRNA silencing AAV

Name
AAV-h-TULP3-shRNA

Cat No
shAAV-226865

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human TULP3.

shAAV-226865

AAV-h-TULP3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TULP3 (tubby like protein 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

TUBL3

Description (Vector)

TULP3 encodes a member of the tubby gene family of bipartite transcription factors. Members of this family have been identified in plants, vertebrates, and invertebrates, and they share a conserved N-terminal transcription activation region and a conserved C-terminal DNA and phosphatidylinositol-phosphate binding region. The encoded protein binds to phosphoinositides in the plasma membrane via its C-terminal region and probably functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis, for instance, induced by G-protein-coupled-receptor signaling. It plays an important role in neuronal development and function. Two transcript variants encoding distinct isoforms have been identified for this gene.

Gene ID

7289

Gene Name (Vector)

tubby like protein 3

Gene Symbol

TULP3

HGNC ID

HGNC:12425

ORF Size (aa)

1329

ORF Size (bp)

1329 bp

RefSeq ID

NM_003324

RefSeq Synonyms

NM_003324, NM_001160408, BC032587,

Species

human

UniGene ID

Hs.655333

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.