human TTYH2 shRNA silencing AAV

Name
AAV-h-TTYH2-shRNA

Cat No
shAAV-226763

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human TTYH2.

shAAV-226763

AAV-h-TTYH2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TTYH2 (tweety family member 2). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

C17orf29

Description (Vector)

TTYH2 encodes a member of the tweety family of proteins. Members of this family function as chloride anion channels. The encoded protein functions as a calcium(2+)-activated large conductance chloride(-) channel, and may play a role in kidney tumorigenesis. Two transcript variants encoding distinct isoforms have been identified for this gene.

Gene ID

94015

Gene Name (Vector)

tweety family member 2

Gene Symbol

TTYH2

HGNC ID

HGNC:13877

ORF Size (aa)

1605

ORF Size (bp)

1605 bp

RefSeq ID

NM_032646

RefSeq Synonyms

NM_052869, NM_032646, NM_001330453, BC107602, BC107492,

Species

human

UniGene ID

Hs.27935

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.