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human TTPA shRNA silencing AAV

Name 
AAV-h-TTPA-shRNA
Cat No 
shAAV-226755
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human TTPA.

shAAV-226755
AAV-h-TTPA-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TTPA (alpha tocopherol transfer protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
alphaTTP; ATTP; AVED; TTP1
Description (Vector)
TTPA encodes a soluble protein that binds alpha-trocopherol, a form of vitamin E, with high selectivity and affinity. This protein plays an important role in regulating vitamin E levels in the body by transporting vitamin E between membrane vesicles and facilitating the secretion of vitamin E from hepatocytes to circulating lipoproteins. Mutations in this gene cause hereditary vitamin E deficiency (ataxia with vitamin E deficiency, AVED) and retinitis pigmentosa.
Gene ID
7274
Gene Name (Vector)
alpha tocopherol transfer protein
Gene Symbol
TTPA
HGNC ID
HGNC:12404
ORF Size (aa)
837
RefSeq ID
NM_000370
RefSeq Synonyms
NM_000370, BC058000,
Species
human
UniGene ID
Hs.69049

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.