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human TTC4 shRNA silencing AAV

Name 
AAV-h-TTC4-shRNA
Cat No 
shAAV-226718
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human TTC4.

shAAV-226718
AAV-h-TTC4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TTC4 (tetratricopeptide repeat domain 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CNS1; tetratricopeptide repeat protein 4; TPR repeat protein 4
Description (eCommerce)
Tetratricopeptide repeat protein 4 (TTC4) contains tetratricopeptide (TPR) repeats, which often mediate protein-protein interactions and chaperone activity. TTC4 interacts with heat shock proteins 70 and 90 [taken from NCBI Entrez Gene (Gene ID: 7268)].
Description (Vector)
TTC4 encodes a protein that contains tetratricopeptide (TPR) repeats. The 34-amino acid tetratricopeptide repeat motifs are found in a variety of proteins and may mediate protein-protein interactions and chaperone activity.
Gene ID
7268
Gene Name (eCommerce)
tetratricopeptide repeat domain 4
Gene Name (Vector)
tetratricopeptide repeat domain 4
Gene Symbol
TTC4
HGNC ID
HGNC:12394
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1164
Protein Name (eCommerce)
Tetratricopeptide repeat protein 4
RefSeq ID
NM_004623
RefSeq Synonyms
NM_004623, NM_001291333, BC001276,
Research Areas
Cell Biology,Translational Control
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
Tetratricopeptide repeat protein 4 (TTC4) contains tetratricopeptide (TPR) repeats, which often mediate protein-protein interactions and chaperone activity. TTC4 interacts with heat shock proteins 70 and 90 [taken from NCBI Entrez Gene (Gene ID: 7268)].
UniGene ID
Hs.412482
UniProt ID (eCommerce)
O95801

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.