human TTBK2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TTBK2.
shAAV-226678
AAV-h-TTBK2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TTBK2 (tau tubulin kinase 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
SCA11; TTBK
Description (Vector)
TTBK2 encodes a serine-threonine kinase that putatively phosphorylates tau and tubulin proteins. Mutations in this gene cause spinocerebellar ataxia type 11 (SCA11); a neurodegenerative disease characterized by progressive ataxia and atrophy of the cerebellum and brainstem.
Gene ID
146057
Gene Name (Vector)
tau tubulin kinase 2
Gene Symbol
TTBK2
HGNC ID
HGNC:19141
ORF Size (aa)
3735
ORF Size (bp)
3735 bp
RefSeq ID
NM_173500
RefSeq Synonyms
NM_173500, BC071556,
Species
human
UniGene ID
Hs.713940
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.