human TSPAN8 shRNA silencing AAV

Name
AAV-h-TSPAN8-shRNA

Cat No
shAAV-226652

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human TSPAN8.

shAAV-226652

AAV-h-TSPAN8-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TSPAN8 (tetraspanin 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CO-029; TM4SF3

Description (Vector)

TSPAN8 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This gene is expressed in different carcinomas. The use of alternate polyadenylation sites has been found for this gene.

Gene ID

7103

Gene Name (Vector)

tetraspanin 8

Gene Symbol

TSPAN8

HGNC ID

HGNC:11855

ORF Size (aa)

714

RefSeq ID

NM_004616

RefSeq Synonyms

NM_004616, BC005246,

Species

human

UniGene ID

Hs.170563

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.