human TSPAN4 shRNA silencing AAV

Name
AAV-h-TSPAN4-shRNA

Cat No
shAAV-226646

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human TSPAN4.

shAAV-226646

AAV-h-TSPAN4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TSPAN4 (tetraspanin 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

NAG-2; NAG2; TETRASPAN; TM4SF7; TSPAN-4

Description (Vector)

TSPAN4 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and is similar in sequence to its family member CD53 antigen. It is known to complex with integrins and other transmembrane 4 superfamily proteins. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene ID

7106

Gene Name (Vector)

tetraspanin 4

Gene Symbol

TSPAN4

HGNC ID

HGNC:11859

ORF Size (aa)

717

RefSeq ID

NM_001025239

RefSeq Synonyms

NM_003271, NM_001025239, NM_001025238, NM_001025237, NM_001025236, NM_001025235, NM_001025234, BC093031, BC019314, BC000389,

Species

human

UniGene ID

Hs.654836

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.