human TSEN34 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TSEN34.
shAAV-226592
AAV-h-TSEN34-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TSEN34 (tRNA splicing endonuclease subunit 34). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
LENG5; PCH2C; SEN34; SEN34L
Description (Vector)
TSEN34 encodes a catalytic subunit of the tRNA splicing endonuclease, which catalyzes the removal of introns from precursor tRNAs. The endonuclease complex is also associated with a pre-mRNA 3-prime end processing factor. A mutation in this gene results in the neurological disorder pontocerebellar hypoplasia type 2. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Gene ID
79042
Gene Name (Vector)
tRNA splicing endonuclease subunit 34
Gene Symbol
TSEN34
HGNC ID
HGNC:15506
ORF Size (aa)
933
RefSeq ID
NM_024075
RefSeq Synonyms
NM_024075, NM_001282333, NM_001282332, NM_001077446, BC020805, BC004530,
Species
human
UniGene ID
Hs.15580
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.