human TRPV4 shRNA silencing AAV

Name 
AAV-h-TRPV4-shRNA
Cat No 
shAAV-226570
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human TRPV4.

shAAV-226570
AAV-h-TRPV4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TRPV4 (transient receptor potential cation channel subfamily V member 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BCYM3; CMT2C; HMSN2C; OTRPC4; SMAL; SPSMA; SSQTL1; TRP12; VRL2; VROAC
Description (Vector)
TRPV4 encodes a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. The encoded protein is a Ca2+-permeable, nonselective cation channel that is thought to be involved in the regulation of systemic osmotic pressure. Mutations in this gene are the cause of spondylometaphyseal and metatropic dysplasia and hereditary motor and sensory neuropathy type IIC. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
59341
Gene Name (Vector)
transient receptor potential cation channel subfamily V member 4
Gene Symbol
TRPV4
HGNC ID
HGNC:18083
ORF Size (aa)
2616
ORF Size (bp)
2616 bp
RefSeq ID
NM_021625
RefSeq Synonyms
NM_147204, NM_021625, NM_001177433, NM_001177431, NM_001177428, BC143315, BC117426,
Species
human
UniGene ID
Hs.506713

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.