human TRNT1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TRNT1.
shAAV-226531
AAV-h-TRNT1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TRNT1 (tRNA nucleotidyl transferase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CCA1; CGI-47; MtCCA; RPEM; SIFD
Description (Vector)
The CCA-adding enzyme TRNT1 (EC 2.7.7.25) is an essential enzyme that catalyzes the addition of the CCA terminus to the 3-prime end of tRNA precursors. This reaction is a fundamental prerequisite for mature tRNAs to become aminoacylated and to participate in protein biosynthesis (Lizano et al., 2007 (PubMed 17204286)).(supplied by OMIM, Aug 2009)
Gene ID
51095
Gene Name (Vector)
tRNA nucleotidyl transferase 1
Gene Symbol
TRNT1
HGNC ID
HGNC:17341
ORF Size (aa)
1218
ORF Size (bp)
1218 bp
RefSeq ID
NM_001302946
RefSeq Synonyms
NM_182916, NM_001302946, BC012537, BC005184,
Species
human
UniGene ID
Hs.567495
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.