human TRMT1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TRMT1.
shAAV-226511
AAV-h-TRMT1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TRMT1 (tRNA methyltransferase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
N(2),N(2)-dimethylguanosine tRNA methyltransferase; TRM1; TRM1 tRNA methyltransferase 1 homolog; tRNA (guanine(26)-N(2))-dimethyltransferase; tRNA 2,2-dimethylguanosine-26 methyltransferase; tRNA methyltransferase 1 homolog; tRNA(guanine-26,N(2)-N(2)) methyltransferase; tRNA(m(2,2)G26)dimethyltransferase
Description (eCommerce)
tRNA 2,2-dimethylguanosine-26 methyltransferas (TRMT1) dimethylates a single guanine residue at position 26 of most tRNAs using S-adenosyl-L-methionine as donor of the methyl groups [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9NXH9].
Gene ID
55621
Gene Name (eCommerce)
tRNA methyltransferase 1
Gene Name (Vector)
tRNA methyltransferase 1
Gene Symbol
TRMT1
HGNC ID
HGNC:25980
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1980
ORF Size (bp)
1980 bp
Protein Name (eCommerce)
tRNA (guanine(26)-N(2))-dimethyltransferase
RefSeq ID
NM_017722
RefSeq Synonyms
NM_017722, NM_001142554, NM_001136035, BC040126, BC018302, BC002492,
Research Areas
Immunology,Metabolism/Metabolic Process,Methyltransferase,RNA Binding,RNA Processing,tRNA Binding,Zinc-finger
Research Areas (Faceted)
immunology,metabolism,cell_biology,genetics,transcription_translation
Species
human
Target Sentence
tRNA 2,2-dimethylguanosine-26 methyltransferas (TRMT1) dimethylates a single guanine residue at position 26 of most tRNAs using S-adenosyl-L-methionine as donor of the methyl groups [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9NXH9].
UniGene ID
Hs.515169
UniProt ID (eCommerce)
Q9NXH9
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.