human TRIB3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TRIB3.
shAAV-226393
AAV-h-TRIB3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TRIB3 (tribbles pseudokinase 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
C20orf97; NIPK; SINK; SKIP3; TRB3
Description (Vector)
TRIB3 is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1.
Gene ID
57761
Gene Name (Vector)
tribbles pseudokinase 3
Gene Symbol
TRIB3
HGNC ID
HGNC:16228
ORF Size (aa)
1077
RefSeq ID
NM_021158
RefSeq Synonyms
NM_021158, NM_001301201, NM_001301196, NM_001301193, NM_001301190, NM_001301188, BC027484, BC019363,
Species
human
UniGene ID
Hs.516826
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.