human TREML1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TREML1.
shAAV-226367
AAV-h-TREML1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TREML1 (triggering receptor expressed on myeloid cells like 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
dJ238O23.3; GLTL1825; PRO3438; TLT-1; TLT1
Description (Vector)
TREML1 is located in a gene cluster on chromosome 6 with the single Ig variable (IgV) domain activating receptors TREM1 (MIM 605085) and TREM2 (MIM 605086), but it has distinct structural and functional properties. TREML1 enhances calcium signaling in an SHP2 (PTPN11; MIM 176876)-dependent manner (Allcock et al., 2003 (PubMed 12645956); Barrow et al., 2004 (PubMed 15128762)).(supplied by OMIM, Mar 2008)
Gene ID
340205
Gene Name (Vector)
triggering receptor expressed on myeloid cells like 1
Gene Symbol
TREML1
HGNC ID
HGNC:20434
ORF Size (aa)
936
RefSeq ID
NM_178174
RefSeq Synonyms
NM_178174, NM_001271808, NM_001271807, BC100946, BC100945, BC100944,
Species
human
UniGene ID
Hs.117331
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.