human TRAM1 shRNA silencing AAV

Name
AAV-h-TRAM1-shRNA

Cat No
shAAV-226342

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human TRAM1.

shAAV-226342

AAV-h-TRAM1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TRAM1 (translocation associated membrane protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

PNAS8; TRAM; TRAMP

Description (Vector)

TRAM1 encodes a multi-pass membrane protein that is part of the mammalian endoplasmic reticulum. The encoded protein influences glycosylation and facilitates the translocation of secretory proteins across the endoplasmic reticulum membrane by regulating which domains of the nascent polypeptide chain are visible to the cytosol during a translocational pause.

Gene ID

23471

Gene Name (Vector)

translocation associated membrane protein 1

Gene Symbol

TRAM1

HGNC ID

HGNC:20568

ORF Size (aa)

1125

RefSeq ID

NM_014294

RefSeq Synonyms

NM_014294, NM_001317805, NM_001317804, BC037738, BC000687,

Species

human

UniGene ID

Hs.491988

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.