human TRAF5 shRNA silencing AAV

Name
AAV-h-TRAF5-shRNA

Cat No
shAAV-226333

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human TRAF5.

shAAV-226333

AAV-h-TRAF5-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TRAF5 (TNF receptor associated factor 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

MGC:39780; RNF84

Description (Vector)

The scaffold protein encoded by this gene is a member of the tumor necrosis factor receptor-associated factor (TRAF) protein family and contains a meprin and TRAF homology (MATH) domain, a RING-type zinc finger, and two TRAF-type zinc fingers. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. This protein is one of the components of a multiple protein complex which binds to tumor necrosis factor (TNF) receptor cytoplasmic domains and mediates TNF-induced activation. Alternate transcriptional splice variants have been characterized.

Gene ID

7188

Gene Name (Vector)

TNF receptor associated factor 5

Gene Symbol

TRAF5

HGNC ID

HGNC:12035

ORF Size (aa)

1674

ORF Size (bp)

1674 bp

RefSeq ID

NM_004619

RefSeq Synonyms

NM_145759, NM_004619, NM_001319207, NM_001033910, BC029600,

Species

human

UniGene ID

Hs.523930

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.