human TPD52L1 shRNA silencing AAV

Name
AAV-h-TPD52L1-shRNA

Cat No
shAAV-226251

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human TPD52L1.

shAAV-226251

AAV-h-TPD52L1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TPD52L1 (tumor protein D52-like 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

D53

Description (Vector)

TPD52L1 encodes a member of the tumor protein D52 (TPD52) family. The encoded protein contains a coiled-coil domain and may form homo- or hetero-dimer with TPD52 family members. The protein is reported to be involved in cell proliferation and calcium signaling. It also interacts with the mitogen-activated protein kinase kinase kinase 5 (MAP3K5/ASK1) and positively regulates MAP3K5-induced apoptosis. Multiple alternatively spliced transcript variants have been observed, but the full-length nature of some variants has not yet been determined.

Gene ID

7164

Gene Name (Vector)

tumor protein D52-like 1

Gene Symbol

TPD52L1

HGNC ID

HGNC:12006

ORF Size (aa)

435

RefSeq ID

NM_003287

RefSeq Synonyms

NM_003287, NM_001318907, NM_001318903, NM_001300994, NM_001292026, NM_001003397, NM_001003396, NM_001003395, BC002375,

Species

human

UniGene ID

Hs.591347

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.