human TNKS shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TNKS.
shAAV-226122
AAV-h-TNKS-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TNKS (tankyrase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ADP-ribosyltransferase diphtheria toxin-like 5; ARTD5; PARP5A; PARP-5a; PARPL; pART5; poly ADP-ribose polymerase 5A; TANK1; tankyrase I; tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase; tankyrase-1; TIN1; TINF1; TNKS1; TNKS-1; TRF1-interacting ankyrin-related ADP-ribose polymerase; TRF1-interacting ankyrin-related ADP-ribose polymerase 1
Description (eCommerce)
Tankyrase-1 is a poly(ADP-ribose) polymerase that localizes to telomeres via its interaction with TRF1. Tankyrase modifies and associates with multiple proteins and appears to be involved in the maintenance of telomere length, sister telomere association, mitotic spindle organization, and trafficking of glut4-containing vesicles.
Gene ID
8658
Gene Name (eCommerce)
tankyrase
Gene Name (Vector)
tankyrase
Gene Symbol
TNKS
HGNC ID
HGNC:11941
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3984
ORF Size (bp)
3984 bp
Protein Name (eCommerce)
Tankyrase-1
RefSeq ID
NM_003747
RefSeq Synonyms
NM_003747, BC098394,
Research Areas
Cell Cycle,Cell Division,Cytoskeleton,Golgi Apparatus,mRNA transport,RNA Transport,Signal Transduction,Telomeric Maintenance,Wnt Signaling
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,signal_transduction,transcription_translation
Species
human
Target Sentence
Tankyrase-1 is a poly(ADP-ribose) polymerase that localizes to telomeres via its interaction with TRF1. Tankyrase modifies and associates with multiple proteins and appears to be involved in the maintenance of telomere length, sister telomere association, mitotic spindle organization, and trafficking of glut4-containing vesicles.
UniGene ID
Hs.370267
UniProt ID (eCommerce)
O95271
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.