human TNK1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TNK1.
shAAV-226120
AAV-h-TNK1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TNK1 (tyrosine kinase non receptor 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
TNK1 belongs to the tyrosine protein kinase family. Tyrosine protein kinases are important regulators of intracellular signal transduction pathways, mediating cellular proliferation, survival, and development. This gene is highly expressed in fetal tissues and at lower levels in few adult tissues, thus may function in signaling pathways utilized broadly during fetal development, and more selectively in adult tissues. It plays a negative regulatory role in the Ras-Raf1-MAPK pathway, and knockout mice have been shown to develop spontaneous tumors, suggesting a role as a tumor suppressor gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
8711
Gene Name (Vector)
tyrosine kinase non receptor 1
Gene Symbol
TNK1
HGNC ID
HGNC:11940
ORF Size (aa)
1986
ORF Size (bp)
1986 bp
RefSeq ID
NM_003985
RefSeq Synonyms
NM_003985, NM_001251902, BC035782,
Species
human
UniGene ID
Hs.203420
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.