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human TNC shRNA silencing AAV

Name 
AAV-h-TNC-shRNA
Cat No 
shAAV-226054
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human TNC.

shAAV-226054
AAV-h-TNC-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TNC (tenascin C). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
150-225; DFNA56; GMEM; GP; HXB; JI; TN; TN-C
Description (Vector)
TNC encodes an extracellular matrix protein with a spatially and temporally restricted tissue distribution. This protein is homohexameric with disulfide-linked subunits, and contains multiple EGF-like and fibronectin type-III domains. It is implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity, and neuronal regeneration.
Gene ID
3371
Gene Name (Vector)
tenascin C
Gene Symbol
TNC
HGNC ID
HGNC:5318
ORF Size (aa)
5784
ORF Size (bp)
5784 bp
RefSeq ID
NM_002160
RefSeq Synonyms
NM_002160, BC151843,
Species
human
UniGene ID
Hs.143250

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.