human TMX1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TMX1.
shAAV-226047
AAV-h-TMX1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TMX1 (thioredoxin related transmembrane protein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
PDIA11; protein disulfide isomerase family A, member 11; thioredoxin domain containing 1; thioredoxin domain-containing protein 1; thioredoxin-related transmembrane protein 1; TMX; transmembrane Trx-related protein; TXNDC; TXNDC1
Description (eCommerce)
Thioredoxin-related transmembrane protein 1 (TMX1) may participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9H3N1].
Description (Vector)
TXNDC1 is a thioredoxin (TXN; see MIM 187700)-related protein with disulfide reductase activity (Matsuo et al., 2001 (PubMed 11152479)).(supplied by OMIM, Mar 2008)
Gene ID
81542
Gene Name (eCommerce)
thioredoxin related transmembrane protein 1
Gene Name (Vector)
thioredoxin related transmembrane protein 1
Gene Symbol
TMX1
HGNC ID
HGNC:15487
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
843
Protein Name (eCommerce)
Thioredoxin-related transmembrane protein 1
RefSeq ID
NM_030755
RefSeq Synonyms
NM_030755, BC056874, BC036460,
Research Areas
Apoptosis,Cell Cycle,DNA Replication,Golgi Apparatus,Immunology,Replication,Signal Transduction,Transcription Factor/Regulator
Research Areas (Faceted)
signal_transduction,cell_biology,cell_cycle,genetics,transcription_translation,cell_biology,immunology,cell_biology,cell_cycle,genetics,transcription_translation
Species
human
Target Sentence
Thioredoxin-related transmembrane protein 1 (TMX1) may participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9H3N1].
UniGene ID
Hs.125221
UniProt ID (eCommerce)
Q9H3N1
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.