human TMOD2 shRNA silencing AAV

Name
AAV-h-TMOD2-shRNA

Cat No
shAAV-225999

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human TMOD2.

shAAV-225999

AAV-h-TMOD2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TMOD2 (tropomodulin 2). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

N-TMOD; NTMOD

Description (Vector)

TMOD2 encodes a neuronal-specific member of the tropomodulin family of actin-regulatory proteins. The encoded protein caps the pointed end of actin filaments preventing both elongation and depolymerization. The capping activity of this protein is dependent on its association with tropomyosin. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene ID

29767

Gene Name (Vector)

tropomodulin 2

Gene Symbol

TMOD2

HGNC ID

HGNC:11872

ORF Size (aa)

924

RefSeq ID

NM_014548

RefSeq Synonyms

NM_014548, NM_001142885, BC064961, BC036184,

Species

human

UniGene ID

Hs.659839

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.