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human TMEM85 shRNA silencing AAV

Name 
AAV-h-TMEM85-shRNA
Cat No 
shAAV-225970
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human EMC4.

shAAV-225970
AAV-h-TMEM85-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human EMC4 (ER membrane protein complex subunit 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
cell proliferation-inducing gene 17 protein; ER membrane protein complex subunit 4; PIG17; TMEM85; transmembrane protein 85
Description (eCommerce)
ER membrane protein complex subunit 4 (EMC4) may mediate anti-apoptotic activity [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q5J8M3].
Gene ID
51234
Gene Name (eCommerce)
ER membrane protein complex subunit 4
Gene Name (Vector)
ER membrane protein complex subunit 4
Gene Symbol
EMC4
HGNC ID
HGNC:28032
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
450
ORF Size (bp)
450 bp
Protein Name (eCommerce)
ER membrane protein complex subunit 4
RefSeq ID
NM_016454
RefSeq Synonyms
NM_016454, NM_001286420, BC002583,
Research Areas
Apoptosis
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
ER membrane protein complex subunit 4 (EMC4) may mediate anti-apoptotic activity [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q5J8M3].
UniGene ID
Hs.250905
UniProt ID (eCommerce)
Q5J8M3

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.