human TM2D3 shRNA silencing AAV

Name
AAV-h-TM2D3-shRNA

Cat No
shAAV-225608

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human TM2D3.

shAAV-225608

AAV-h-TM2D3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TM2D3 (TM2 domain containing 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

BLP2

Description (Vector)

TM2D3 contains a structural module related to that of the seven transmembrane domain G protein-coupled receptor superfamily. This protein has sequence and structural similarities to the beta-amyloid binding protein (BBP), but, unlike BBP, it does not regulate a response to beta-amyloid peptide. This protein may have regulatory roles in cell death or proliferation signal cascades. Several alternatively spliced transcript variants of this gene are described but the full length nature of some variants has not been determined. Multiple polyadenylation sites have been found in this gene.

Gene ID

80213

Gene Name (Vector)

TM2 domain containing 3

Gene Symbol

TM2D3

HGNC ID

HGNC:24128

ORF Size (aa)

666

RefSeq ID

NM_025141

RefSeq Synonyms

NM_078474, NM_025141, NM_001308026, NM_001307960, BC008873, BC006150,

Species

human

UniGene ID

Hs.596698

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.