human TINP1 shRNA silencing AAV

Name 
AAV-h-TINP1-shRNA
Cat No 
shAAV-225539
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human NSA2.

shAAV-225539
AAV-h-TINP1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NSA2 (NSA2, ribosome biogenesis homolog). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CDK105; hairy cell leukemia protein 1; HCLG1; HCL-G1; HUSSY29; HUSSY-29; ribosome biogenesis protein NSA2 homolog; TGF beta-inducible nuclear protein 1; TGF-beta inducible nuclear protein; TGF-beta-inducible nuclear protein 1; TINP1
Description (eCommerce)
Ribosome biogenesis protein NSA2 homolog, also known as hairy cell leukemia protein 1, is encoded for by the gene NSA2. The product of NSA2, also called TINP1, is a nucleolar protein involved in cell cycle regulation and proliferation. Hairy cell leukemia protein 1 is found at elevated levels in diabetic nephropathy [taken from NCBI Entrez Gene (Gene ID: 10412)].
Gene ID
10412
Gene Name (eCommerce)
NSA2, ribosome biogenesis homolog
Gene Name (Vector)
NSA2, ribosome biogenesis homolog
Gene Symbol
NSA2
HGNC ID
HGNC:30728
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
783
ORF Size (bp)
783 bp
Protein Name (eCommerce)
Ribosome biogenesis protein NSA2 homolog
RefSeq ID
NM_014886
RefSeq Synonyms
NM_014886, NM_001271665, BC005288,
Research Areas
RNA Processing
Research Areas (Faceted)
cell_biology,genetics,transcription_translation
Species
human
Target Sentence
Ribosome biogenesis protein NSA2 homolog, also known as hairy cell leukemia protein 1, is encoded for by the gene NSA2. The product of NSA2, also called TINP1, is a nucleolar protein involved in cell cycle regulation and proliferation. Hairy cell leukemia protein 1 is found at elevated levels in diabetic nephropathy [taken from NCBI Entrez Gene (Gene ID: 10412)].
UniGene ID
Hs.482526
UniProt ID (eCommerce)
O95478

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.