human TIAM2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TIAM2.
shAAV-225490
AAV-h-TIAM2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TIAM2 (T-cell lymphoma invasion and metastasis 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
STEF; TIAM-2
Description (Vector)
TIAM2 encodes a guanine nucleotide exchange factor. A highly similar mouse protein specifically activates ras-related C3 botulinum substrate 1, converting this Rho-like guanosine triphosphatase (GTPase) from a guanosine diphosphate-bound inactive state to a guanosine triphosphate-bound active state. The encoded protein may play a role in neural cell development. Alternatively spliced transcript variants encoding different isoforms have been described.
Gene ID
26230
Gene Name (Vector)
T-cell lymphoma invasion and metastasis 2
Gene Symbol
TIAM2
HGNC ID
HGNC:11806
ORF Size (aa)
5106
ORF Size (bp)
5106 bp
RefSeq ID
NM_012454
RefSeq Synonyms
NM_012454, NM_001010927, BC137275,
Species
human
UniGene ID
Hs.586279
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.