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human THEM2 shRNA silencing AAV

Name 
AAV-h-THEM2-shRNA
Cat No 
shAAV-225439
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ACOT13.

shAAV-225439
AAV-h-THEM2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ACOT13 (acyl-CoA thioesterase 13). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HT012; PNAS-27; THEM2
Description (Vector)
ACOT13 encodes a member of the thioesterase superfamily. In humans, the protein co-localizes with microtubules and is essential for sustained cell proliferation. The orthologous mouse protein forms a homotetramer and is associated with mitochondria. The mouse protein functions as a medium- and long-chain acyl-CoA thioesterase. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
55856
Gene Name (Vector)
acyl-CoA thioesterase 13
Gene Symbol
ACOT13
HGNC ID
HGNC:20999
ORF Size (aa)
423
ORF Size (bp)
423 bp
RefSeq ID
NM_018473
RefSeq Synonyms
NM_018473, NM_001160094, BC000894,
Species
human
UniGene ID
Hs.9676

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.