human PNPLA8 shRNA silencing AAV

Name 
AAV-h-PNPLA8-shRNA
Cat No 
shAAV-225425
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PNPLA8.

shAAV-225425
AAV-h-PNPLA8-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PNPLA8 (patatin like phospholipase domain containing 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
IPLA2-2; IPLA2G; iPLA2gamma; MMLA; PNPLA-gamma
Description (Vector)
PNPLA8 encodes a member of the patatin-like phospholipase domain containing protein family. Members of this family are phospholipases which catalyze the cleavage of fatty acids from membrane phospholipids. The product of this gene is a calcium-independent phospholipase. A pseudogene of this gene is located on the X chromosome. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
50640
Gene Name (Vector)
patatin like phospholipase domain containing 8
Gene Symbol
PNPLA8
HGNC ID
HGNC:28900
ORF Size (aa)
2349
ORF Size (bp)
2349 bp
RefSeq ID
NM_015723
RefSeq Synonyms
NM_015723, NM_001256011, NM_001256010, NM_001256009, NM_001256008, NM_001256007, BC032999,
Species
human
UniGene ID
Hs.617340

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.