human THAP11 shRNA silencing AAV

Name 
AAV-h-THAP11-shRNA
Cat No 
shAAV-225421
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human THAP11.

shAAV-225421
AAV-h-THAP11-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human THAP11 (THAP domain containing 11). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CTG-B43a; CTG-B45d; HRIHFB2206; RONIN; THAP domain-containing protein 11
Description (eCommerce)
Ronin is also known as THAP domain containing 11 (THAP). Ronin was identified as a candidate pluripotency factor in mouse ES cells. Ronin functions is a sequence-specific DNA-binding factor that represses gene expression in pluripotent ES cells by directly binding to key genetic loci and recruiting epigenetic modifiers.
Description (Vector)
THAP11 contains a THAP domain, which is a conserved DNA-binding domain that has striking similarity to the site-specific DNA-binding domain (DBD) of Drosophila P element transposases.
Gene ID
57215
Gene Name (eCommerce)
THAP domain containing 11
Gene Name (Vector)
THAP domain containing 11
Gene Symbol
THAP11
HGNC ID
HGNC:23194
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
942
Protein Name (eCommerce)
THAP domain-containing protein 11
RefSeq ID
NM_020457
RefSeq Synonyms
NM_020457, BC012182,
Research Areas
Cell Cycle,Transcription Factor/Regulator,Zinc-finger
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,transcription_translation
Species
human
Target Sentence
Ronin is also known as THAP domain containing 11 (THAP). Ronin was identified as a candidate pluripotency factor in mouse ES cells. Ronin functions is a sequence-specific DNA-binding factor that represses gene expression in pluripotent ES cells by directly binding to key genetic loci and recruiting epigenetic modifiers.
UniGene ID
Hs.632200
UniProt ID (eCommerce)
Q96EK4

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.