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human TGM5 shRNA silencing AAV

Name 
AAV-h-TGM5-shRNA
Cat No 
shAAV-225405
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human TGM5.

shAAV-225405
AAV-h-TGM5-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TGM5 (transglutaminase 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
PSS2; TGASE5; TGASEX; TGM6; TGMX; TGX
Description (Vector)
TGM5 encodes a member of the transglutaminase family. The encoded protein catalyzes formation of protein cross-links between glutamine and lysine residues, often resulting in stabilization of protein assemblies. This reaction is calcium dependent. Mutations in this gene have been associated with acral peeling skin syndrome.
Gene ID
9333
Gene Name (Vector)
transglutaminase 5
Gene Symbol
TGM5
HGNC ID
HGNC:11781
ORF Size (aa)
2163
ORF Size (bp)
2163 bp
RefSeq ID
NM_004245
RefSeq Synonyms
NM_201631, NM_004245, BC122859, BC119009,
Species
human
UniGene ID
Hs.129719

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.