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human TFEC shRNA silencing AAV

Name 
AAV-h-TFEC-shRNA
Cat No 
shAAV-225359
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human TFEC.

shAAV-225359
AAV-h-TFEC-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TFEC (transcription factor EC). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
bHLHe34; hTFEC-L; TCFEC; TFE-C; TFEC-L; TFECL
Description (Vector)
TFEC encodes a member of the micropthalmia (MiT) family of basic helix-loop-helix leucine zipper transcription factors. MiT transcription factors regulate the expression of target genes by binding to E-box recognition sequences as homo- or heterodimers, and play roles in multiple cellular processes including survival, growth and differentiation. The encoded protein is a transcriptional activator of the nonmuscle myosin II heavy chain-A gene, and may also co-regulate target genes in osteoclasts as a heterodimer with micropthalmia-associated transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
22797
Gene Name (Vector)
transcription factor EC
Gene Symbol
TFEC
HGNC ID
HGNC:11754
ORF Size (aa)
594
RefSeq ID
NM_012252
RefSeq Synonyms
NM_012252, NM_001244583, NM_001018058, BC029891,
Species
human
UniGene ID
Hs.125962

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.