human TFCP2 shRNA silencing AAV

Name 
AAV-h-TFCP2-shRNA
Cat No 
shAAV-225353
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human TFCP2.

shAAV-225353
AAV-h-TFCP2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TFCP2 (transcription factor CP2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
LBP1C; LSF; LSF1D; SEF; TFCP2C
Description (Vector)
TFCP2 encodes a transcription factor that binds the alpha-globin promoter and activates transcription of the alpha-globin gene. The encoded protein regulates erythroid gene expression, plays a role in the transcriptional switch of globin gene promoters, and it activates many other cellular and viral gene promoters. The gene product interacts with certain inflammatory response factors, and polymorphisms of this gene may be involved in the pathogenesis of Alzheimer's disease.
Gene ID
7024
Gene Name (Vector)
transcription factor CP2
Gene Symbol
TFCP2
HGNC ID
HGNC:11748
ORF Size (aa)
1509
ORF Size (bp)
1509 bp
RefSeq ID
NM_005653
RefSeq Synonyms
NM_005653, NM_001173453, NM_001173452, BC003634,
Species
human
UniGene ID
Hs.48849

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.