human TDRD3 shRNA silencing AAV

Name
AAV-h-TDRD3-shRNA

Cat No
shAAV-225270

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human TDRD3.

shAAV-225270

AAV-h-TDRD3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TDRD3 (tudor domain containing 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

tudor domain-containing protein 3

Description (eCommerce)

Tudor domain-containing protein 3 (TDRD3) bears one tudor domain and an ubiquitin associated domain (UBA). Tudor domains interact with arginine-glycine-rich motifs in a methylarginine-dependent manner. TDRD3 has been shown to localize to cytoplasmic stress granules and may play a role in the regulation of mRNA translation.

Gene ID

81550

Gene Name (eCommerce)

tudor domain containing 3

Gene Name (Vector)

tudor domain containing 3

Gene Symbol

TDRD3

HGNC ID

HGNC:20612

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

1953

ORF Size (bp)

1953 bp

Protein Name (eCommerce)

Tudor domain-containing protein 3

RefSeq ID

NM_030794

RefSeq Synonyms

NM_030794, NM_001146071, NM_001146070, BC060876, BC030514,

Research Areas

Chromatin Remodeling,Translational Control,Ubiquitination

Research Areas (Faceted)

cell_biology,genetics,transcription_translation

Species

human

Target Sentence

Tudor domain-containing protein 3 (TDRD3) bears one tudor domain and an ubiquitin associated domain (UBA). Tudor domains interact with arginine-glycine-rich motifs in a methylarginine-dependent manner. TDRD3 has been shown to localize to cytoplasmic stress granules and may play a role in the regulation of mRNA translation.

UniGene ID

Hs.525061

UniProt ID (eCommerce)

Q9H7E2

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.