human TBX22 shRNA silencing AAV

Name
AAV-h-TBX22-shRNA

Cat No
shAAV-225159

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human TBX22.

shAAV-225159

AAV-h-TBX22-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TBX22 (T-box 22). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ABERS; CLPA; CPX; dJ795G23.1; TBXX

Description (Vector)

TBX22 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene have been associated with the inherited X-linked disorder, Cleft palate with ankyloglossia, and it is believed to play a major role in human palatogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene ID

50945

Gene Name (Vector)

T-box 22

Gene Symbol

TBX22

HGNC ID

HGNC:11600

ORF Size (aa)

1563

ORF Size (bp)

1563 bp

RefSeq ID

NM_016954

RefSeq Synonyms

NM_016954, NM_001303475, NM_001109879, NM_001109878, BC014194,

Species

human

UniGene ID

Hs.374253

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.