human TBC1D24 shRNA silencing AAV

Name
AAV-h-TBC1D24-shRNA

Cat No
shAAV-225089

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human TBC1D24.

shAAV-225089

AAV-h-TBC1D24-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TBC1D24 (TBC1 domain family member 24). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

DFNA65; DFNB86; DOORS; EIEE16; FIME; TLDC6

Description (Vector)

TBC1D24 encodes a protein with a conserved domain, referred to as the TBC domain, characteristic of proteins which interact with GTPases. TBC domain proteins may serve as GTPase-activating proteins for a particular group of GTPases, the Rab (Ras-related proteins in brain) small GTPases which are involved in the regulation of membrane trafficking. Mutations in this gene are associated with familial infantile myoclonic epilepsy. Alternative splicing results in multiple transcript variants.

Gene ID

57465

Gene Name (Vector)

TBC1 domain family member 24

Gene Symbol

TBC1D24

HGNC ID

HGNC:29203

ORF Size (aa)

1680

ORF Size (bp)

1680 bp

RefSeq ID

NM_020705

RefSeq Synonyms

NM_020705, NM_001199107, BC127015, BC127014, BC112389,

Species

human

UniGene ID

Hs.353087

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.