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human TAGLN2 shRNA silencing AAV

Name 
AAV-h-TAGLN2-shRNA
Cat No 
shAAV-224947
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human TAGLN2.

shAAV-224947
AAV-h-TAGLN2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TAGLN2 (transgelin 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
epididymis secretory sperm binding protein; epididymis tissue protein Li 7e; HA1756; SM22-alpha homolog; transgelin-2
Description (eCommerce)
Transgelin 2 (TAGLN2) is similar to the protein transgelin, which is one of the earliest markers of differentiated smooth muscle. The specific function of this protein has not yet been determined, although it is thought to be a tumor suppressor [taken from NCBI Entrez Gene (Gene ID: 8407)].
Description (Vector)
TAGLN2 is a homolog of the protein transgelin, which is one of the earliest markers of differentiated smooth muscle. The function of this protein has not yet been determined.
Gene ID
8407
Gene Name (eCommerce)
transgelin 2
Gene Name (Vector)
transgelin 2
Gene Symbol
TAGLN2
HGNC ID
HGNC:11554
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
600
Protein Name (eCommerce)
Transgelin-2
RefSeq ID
NM_003564
RefSeq Synonyms
NM_003564, NM_001277224, NM_001277223, BC009357, BC002616,
Research Areas
EGFR Signaling,Signal Transduction,Tumor Suppressors/Oncoproteins
Research Areas (Faceted)
cancer,signal_transduction
Species
human
Target Sentence
Transgelin 2 (TAGLN2) is similar to the protein transgelin, which is one of the earliest markers of differentiated smooth muscle. The specific function of this protein has not yet been determined, although it is thought to be a tumor suppressor [taken from NCBI Entrez Gene (Gene ID: 8407)].
UniGene ID
Hs.517168
UniProt ID (eCommerce)
P37802

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.