human TAF10 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TAF10.
shAAV-224910
AAV-h-TAF10-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TAF10 (TATA-box binding protein associated factor 10). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
TAF2A; TAF2H; TAFII30
Description (Vector)
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the small subunits of TFIID that is associated with a subset of TFIID complexes. Studies with human and mammalian cells have shown that this subunit is required for transcriptional activation by the estrogen receptor, for progression through the cell cycle, and may also be required for certain cellular differentiation programs.
Gene ID
6881
Gene Name (Vector)
TATA-box binding protein associated factor 10
Gene Symbol
TAF10
HGNC ID
HGNC:11543
ORF Size (aa)
657
RefSeq ID
NM_006284
RefSeq Synonyms
NM_006284, BC012088,
Species
human
UniGene ID
Hs.5158
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.