human SYTL1 shRNA silencing AAV

Name 
AAV-h-SYTL1-shRNA
Cat No 
shAAV-224863
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SYTL1.

shAAV-224863
AAV-h-SYTL1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SYTL1 (synaptotagmin like 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
50
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
exophilin-7; JFC1; NADPH oxidase-related, C2 domain-containing protein; Protein JFC1; SLP1; synaptotagmin-like protein 1
Description (eCommerce)
Synaptotagmin-like protein 1 (SYTL1) may play a role in vesicle trafficking (By similarity). SYTL1 binds phosphatidylinositol 3,4,5-trisphosphate. It acts as a RAB27A effector protein and may play a role in cytotoxic granule exocytosis in lymphocytes (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8IYJ3].
Gene ID
84958
Gene Name (eCommerce)
synaptotagmin like 1
Gene Name (Vector)
synaptotagmin like 1
Gene Symbol
SYTL1
HGNC ID
HGNC:15584
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1374
ORF Size (bp)
1374 bp
Protein Name (eCommerce)
Synaptotagmin-like protein 1
RefSeq ID
NM_032872
RefSeq Synonyms
NM_032872, NM_001193308, BC035725, BC015764,
Research Areas
Bladder Cancer,Cancer,Neurobiology
Research Areas (Faceted)
cancer,neurobiology
Species
human
Target Sentence
Synaptotagmin-like protein 1 (SYTL1) may play a role in vesicle trafficking (By similarity). SYTL1 binds phosphatidylinositol 3,4,5-trisphosphate. It acts as a RAB27A effector protein and may play a role in cytotoxic granule exocytosis in lymphocytes (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8IYJ3].
UniGene ID
Hs.469175
UniProt ID (eCommerce)
Q8IYJ3

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.