human SYK shRNA silencing AAV

Cat. No: shAAV-224803

Availability: 4-5 weeks

Name: AAV-h-SYK-shRNA

This is an AAV expressing shRNA for silencing of Human SYK.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SYK
Gene Name: spleen associated tyrosine kinase
Gene ID: 6850
Gene Synonyms: p72-Syk
ORF Size: 1839 bp
RefSeq#: NM_003177
Gene Description: SYK encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.371720
HGNC ID: HGNC:11491