human SUV39H1 shRNA silencing AAV

Cat. No: shAAV-224768

Availability: 4-5 weeks

Name: AAV-h-SUV39H1-shRNA

This is an AAV expressing shRNA for silencing of Human SUV39H1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SUV39H1
Gene Name: suppressor of variegation 3-9 homolog 1
Gene ID: 6839
Gene Synonyms: H3-K9-HMTase 1; KMT1A; MG44; SUV39H
ORF Size: 1239 bp
RefSeq#: NM_003173
Gene Description: SUV39H1 is a member of the suppressor of variegation 3-9 homolog family and encodes a protein with a chromodomain and a C-terminal SET domain. This nuclear protein moves to the centromeres during mitosis and functions as a histone methyltransferase, methylating Lys-9 of histone H3. Overall, it plays a vital role in heterochromatin organization, chromosome segregation, and mitotic progression.
UniGene ID: Hs.522639
HGNC ID: HGNC:11479