human SUMO3 shRNA silencing AAV

Name
AAV-h-SUMO3-shRNA

Cat No
shAAV-224744

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human SUMO3.

shAAV-224744

AAV-h-SUMO3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SUMO3 (small ubiquitin-like modifier 3). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

SMT3A; Smt3B; SMT3H1; SUMO-3

Description (Vector)

SUMO proteins, such as SUMO3, and ubiquitin (see MIM 191339) posttranslationally modify numerous cellular proteins and affect their metabolism and function. However, unlike ubiquitination, which targets proteins for degradation, sumoylation participates in a number of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability (Su and Li, 2002 (PubMed 12383504)).(supplied by OMIM, Mar 2008)

Gene ID

6612

Gene Name (Vector)

small ubiquitin-like modifier 3

Gene Symbol

SUMO3

HGNC ID

HGNC:11124

ORF Size (aa)

312

RefSeq ID

NM_006936

RefSeq Synonyms

NM_006936, NM_001286416, BC008420, BC000036,

Species

human

UniGene ID

Hs.474005

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.