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human SUMF2 shRNA silencing AAV

Name 
AAV-h-SUMF2-shRNA
Cat No 
shAAV-224730
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SUMF2.

shAAV-224730
AAV-h-SUMF2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SUMF2 (sulfatase modifying factor 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
86
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
pFGE
Description (Vector)
The catalytic sites of sulfatases are only active if they contain a unique amino acid, C-alpha-formylglycine (FGly). The FGly residue is posttranslationally generated from a cysteine by enzymes with FGly-generating activity. The gene described in this record is a member of the sulfatase-modifying factor family and encodes a protein with a DUF323 domain that localizes to the lumen of the endoplasmic reticulum. This protein has low levels of FGly-generating activity but can heterodimerize with another family member - a protein with high levels of FGly-generating activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Gene ID
25870
Gene Name (Vector)
sulfatase modifying factor 2
Gene Symbol
SUMF2
HGNC ID
HGNC:20415
ORF Size (aa)
906
RefSeq ID
NM_015411
RefSeq Synonyms
NM_015411, NM_001146333, NM_001130069, NM_001042470, NM_001042469, BC111092, BC084539, BC065222, BC015600,
Species
human
UniGene ID
Hs.279696

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.