human STEAP2 shRNA silencing AAV

Name 
AAV-h-STEAP2-shRNA
Cat No 
shAAV-224556
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human STEAP2.

shAAV-224556
AAV-h-STEAP2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human STEAP2 (STEAP2 metalloreductase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
IPCA1; PCANAP1; PUMPCn; STAMP1; STMP
Description (Vector)
STEAP2 is a member of the STEAP family and encodes a multi-pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Gene ID
261729
Gene Name (Vector)
STEAP2 metalloreductase
Gene Symbol
STEAP2
HGNC ID
HGNC:17885
ORF Size (aa)
1473
ORF Size (bp)
1473 bp
RefSeq ID
NM_152999
RefSeq Synonyms
NM_152999, NM_001244946, NM_001244945, NM_001244944, NM_001040666, NM_001040665, BC148824, BC146341,
Species
human
UniGene ID
Hs.489051

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.