human STAG1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human STAG1.
shAAV-224496
AAV-h-STAG1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human STAG1 (stromal antigen 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
cohesin subunit SA-1; MRD47; nuclear protein stromal antigen 1; SA1; SCC3 homolog 1; SCC3A; Stromal antigen 1
Description (eCommerce)
SA1 is a component of the multisubunit cohesin complex. Cohesin functions to hold sister chromatids together during meiosis and mitosis and ensure proper segregation of chromosomes. SA1 has also been identified as a mediator of p53 induced apoptosis.
Description (Vector)
STAG1 is a member of the SCC3 family and is expressed in the nucleus. It encodes a component of cohesin, a multisubunit protein complex that provides sister chromatid cohesion along the length of a chromosome from DNA replication through prophase and prometaphase, after which it is dissociated in preparation for segregation during anaphase.
Gene ID
10274
Gene Name (eCommerce)
stromal antigen 1
Gene Name (Vector)
stromal antigen 1
Gene Symbol
STAG1
HGNC ID
HGNC:11354
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3666
ORF Size (bp)
3666 bp
Protein Name (eCommerce)
Cohesin subunit SA-1
RefSeq ID
NM_005862
RefSeq Synonyms
NM_005862, BC064699,
Research Areas
Cell Cycle,Cell Division,Meiosis
Research Areas (Faceted)
cell_biology,cell_cycle,developmental_biology,genetics
Species
human
Target Sentence
SA1 is a component of the multisubunit cohesin complex. Cohesin functions to hold sister chromatids together during meiosis and mitosis and ensure proper segregation of chromosomes. SA1 has also been identified as a mediator of p53 induced apoptosis.
UniGene ID
Hs.412586
UniProt ID (eCommerce)
Q8WVM7
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.