human ST8SIA5 shRNA silencing AAV

Name
AAV-h-ST8SIA5-shRNA

Cat No
shAAV-224487

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human ST8SIA5.

shAAV-224487

AAV-h-ST8SIA5-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ST8SIA5 (ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

SIAT8-E; SIAT8E; ST8SiaV

Description (Vector)

ST8SIA5 is a type II membrane protein that may be present in the Golgi apparatus. The encoded protein, which is a member of glycosyltransferase family 29, may be involved in the synthesis of gangliosides GD1c, GT1a, GQ1b, and GT3 from GD1a, GT1b, GM1b, and GD3, respectively.

Gene ID

29906

Gene Name (Vector)

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5

Gene Symbol

ST8SIA5

HGNC ID

HGNC:17827

ORF Size (aa)

1131

ORF Size (bp)

1131 bp

RefSeq ID

NM_013305

RefSeq Synonyms

NM_013305, NM_001307987, NM_001307986, BC108911, BC108910,

Species

human

UniGene ID

Hs.465025

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.