human SSTR5 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SSTR5.
shAAV-224411
AAV-h-SSTR5-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SSTR5 (somatostatin receptor 5). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
SS-5-R
Description (Vector)
Somatostatin and its related peptide cortistatin exert multiple biological actions on normal and tumoral tissue targets by interacting with somatostatin receptors (SSTRs). The protein encoded by this gene is one of the SSTRs, which is a multi-pass membrane protein and belongs to the G-protein coupled receptor 1 family. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase, and different regions of this receptor molecule are required for the activation of different signaling pathways. A mutation in this gene results in somatostatin analog resistance. Alternatively spliced transcript variants have been identified in this gene.
Gene ID
6755
Gene Name (Vector)
somatostatin receptor 5
Gene Symbol
SSTR5
HGNC ID
HGNC:11334
ORF Size (aa)
1095
RefSeq ID
NM_001053
RefSeq Synonyms
NM_001172560, NM_001053, BC146576, BC141553,
Species
human
UniGene ID
Hs.449840
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.