human SRPRB shRNA silencing AAV

Cat. No: shAAV-224360

Availability: 4-5 weeks

Name: AAV-h-SRPRB-shRNA

This is an AAV expressing shRNA for silencing of Human SRPRB.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SRPRB
Gene Name: SRP receptor beta subunit
Gene ID: 58477
Gene Synonyms: APMCF1
ORF Size: 816 bp
RefSeq#: NM_021203
Gene Description: SRPRB has similarity to mouse protein which is a subunit of the signal recognition particle receptor (SR). This subunit is a transmembrane GTPase belonging to the GTPase superfamily. It anchors alpha subunit, a peripheral membrane GTPase, to the ER membrane. SR is required for the cotranslational targeting of both secretory and membrane proteins to the ER membrane.
UniGene ID: Hs.12152
HGNC ID: HGNC:24085