human SRI shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SRI.
shAAV-224331
AAV-h-SRI-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SRI (sorcin). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CP-22; CP22; SCN; V19
Description (Vector)
SRI encodes a calcium-binding protein with multiple E-F hand domains that relocates from the cytoplasm to the sarcoplasmic reticulum in response to elevated calcium levels. In addition to regulating intracellular calcium homeostasis it also modulates excitation-contraction coupling in the heart. Alternative splicing results in multiple transcript variants encoding distinct proteins. Multiple pseudogenes exist for this gene.
Gene ID
6717
Gene Name (Vector)
sorcin
Gene Symbol
SRI
HGNC ID
HGNC:11292
ORF Size (aa)
597
RefSeq ID
NM_003130
RefSeq Synonyms
NM_198901, NM_003130, NM_001256892, NM_001256891, BC011025,
Species
human
UniGene ID
Hs.489040
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.