human SRFBP1 shRNA silencing AAV

Name 
AAV-h-SRFBP1-shRNA
Cat No 
shAAV-224325
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SRFBP1.

shAAV-224325
AAV-h-SRFBP1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SRFBP1 (serum response factor binding protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BUD22; BUD22 homolog; P49; p49/STRAP; Rlb1; serum response factor-binding protein 1; SRF-dependent transcription regulation-associated protein; STRAP
Description (eCommerce)
p49/STRAP interacts with serum response factor (SRF) and is also known as serum response factor-binding protein 1 and SRF-dependent transcription regulation-associated protein. p49/STRAP may be involved in regulating transcriptional activation of cardiac genes during the aging process, and may play a role in biosynthesis and/or processing of SLC2A4 in adipose cells.
Gene ID
153443
Gene Name (eCommerce)
serum response factor binding protein 1
Gene Name (Vector)
serum response factor binding protein 1
Gene Symbol
SRFBP1
HGNC ID
HGNC:26333
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1290
ORF Size (bp)
1290 bp
Protein Name (eCommerce)
Serum response factor-binding protein 1
RefSeq ID
NM_152546
RefSeq Synonyms
NM_152546, BC031222,
Research Areas
Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
p49/STRAP interacts with serum response factor (SRF) and is also known as serum response factor-binding protein 1 and SRF-dependent transcription regulation-associated protein. p49/STRAP may be involved in regulating transcriptional activation of cardiac genes during the aging process, and may play a role in biosynthesis and/or processing of SLC2A4 in adipose cells.
UniGene ID
Hs.107622
UniProt ID (eCommerce)
Q8NEF9

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.